Is spraying one side of a wasp/hornet nest enough?

I have a wasp/hornet nest in the bushes, so tonight I sprayed it. I could only spray it from one angle though - the front with the hole. I sprayed enough that the can ran out. Is that enough to kill all of the wasps/hornets, if I could only hit the front side?

 

I don't think I've ever tried to hit a wasp nest from all sides but always found the spray effective. If it's a hornet nest and you got spray inside the entrance I think that should be enough.

 

I have never used the whole can on one nest, If you got the queen nest will die.

 

That's more than enough assuming that even a small amount got inside the nest. When you mention "hole" that makes me think that it is really a hornet nest which looks much like a paper football, except when it's small and it looks like a softball. Those are trickier than treating an open-faced wasp nest. The results will tell you if it is enough. Give it several days before you re-assess the effectiveness as the spray does have residual effects, though it is quite repellent, too.

Assuming it is a hornet nest and is covered with paper, there are "vents" near the top of the nest that help with air flow. It's good to spray up there, too.